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Observatory on current biosafety practice in European Oncology

More information on the observatory, including the data and conclusions by country, can be found here

A report commissioned by the European Biosafety Network has shed light on conditions in hospitals across the EU which could be endangering the lives of nurses, pharmacists, other hospital staff, carers and patients.  The report was launched on 7th March at a roundtable on preventing exposure to hazardous drugs in healthcare, held in the European Parliament in Brussels attended by MEPs, unions, employers, professional associations, representatives of Member States and the European Commission.

The report exposes deficiencies in the cleanliness and working conditions of oncology outpatient units where hazardous cytotoxic drugs are used mainly by nurses to treat cancer: with 18% of the respondents having no policy for cleaning these areas, 45% failing to carry out standard routine contamination monitoring and 42% of staff not receiving regular medical testing. These basic measures are essential for protecting healthcare staff, carers and patients from exposure to hazardous drugs which can also cause them to contract cancer, particularly leukaemia, malignancy, birth defects and miscarriages.

The report is based on a survey of hospital pharmacists and oncology nurses which focused particularly on exposure to cytotoxic drugs, vital in the treatment of cancers, but which are also carcinogenic and highly dangerous to staff, patients and their families. Exposure to cytotoxic drugs can cause acute skin and eye irritations, as well as nausea, headaches, and dizziness. Exposure has also been linked to complications during pregnancy, including higher incidences of spontaneous abortions, congenital malformations, low birth weight, and infertility. Studies show that nurses exposed to cytotoxic drugs are twice as likely to miscarry, and that hospital workers handling cytotoxic drugs are three times more likely to develop malignancy.

The report found that:

  • 23% of the oncology outpatient units failed to provide training policies for staff handling hazardous drugs.
  • Regular medical testing is only carried out regularly in 58% of the units.
  • Regular monitoring of surface contamination is only carried out in 55% of oncology outpatient units.
  • 14% of the preparation of hazardous drugs and 59% of the spiking of medical bags does not take place in pharmacies, meaning that many nurses on wards are exposed to the risk of spillages and leakages.

The report, entitled “Observatory on current biosafety practice in European Oncology,” was commissioned by the European Biosafety Network, a European group set up by nurses and trade unionists in healthcare that promotes and campaigns for the health and safety of workers and patients. The survey was conducted by Ipsos MORI, the international survey research organisation, and covers 14 countries across the EU, including the Spain, Portugal, France, Italy, Denmark, Latvia, Estonia, Netherlands, UK, Belgium, Ireland, Poland, Germany, Sweden.

The report also exposed failures in hospital pharmacies, where many of the hazardous drugs used in treatments are prepared and stored. 11% of pharmacies surveyed had no regular decontamination protocol for areas where hazardous drugs were handled, and nearly half of were failing to monitor surfaces for contamination. Further, it was revealed that medical devices such as syringes, needles and spikes were still in widespread use, despite the availability and recommendation of up-to-date devices, such as closed system drug transfer devices (CSTDs), that provide superior exposure prevention through closed systems.

The report includes the following recommendations from the European Biosafety Network for healthcare regulators, policy makers and administrators:

  • Increase the use of risk assessments and promote the active recording of incidents involving hazardous drugs.
  • Regular monitoring of surface contamination should be universal, more frequent and more comprehensive.
  • Ensure that decontamination and cleaning protocols are in place in all pharmacies and oncology nursing wards.
  • Increase medical surveillance and regular medical testing for healthcare workers.
  • Ensure that preparation of hazardous drugs and spiking of medication bags is carried out in the hospital pharmacy not on the wards.
  • Ensure that sterile rooms used in the preparation of hazardous drugs are equipped with either a Biological Safety Cabinet (BSC) or an Aseptic Isolator (AI), and that closed systems drug transfer devices (CSTDs) are the primary device used to ensure a closed system in the preparation and administration of hazardous drugs.
  • Hazardous drugs should be included in the Carcinogens and Mutagens Directive EU 2004/37, combined with mandatory European guidelines and a European list of hazardous drugs.

For inquiries, including press inquiries, please contact Henry Bettley at